Will this trial be stopped early?
Look up any Phase 1–3 drug trial on ClinicalTrials.gov that started in 2008 or later. You'll see its termination-risk score, how it ranks against the trials running now, and what moved the score.
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How good is it?
Checked against leakage: scored with registry records as they stood at each trial's start (from 25 archived snapshots), the AUC changes by +0.001 (95% CI -0.001 to +0.003) on 18,568 trials. Fields found edited after start are left out of the model.
When, not just whether: a competing-risks survival model ranks which trials terminate within 2 years at time-AUC 0.649 (95% CI 0.629–0.672), ahead of the yes/no model (0.613), with still-running trials handled as censored. Termination risk is rising: 5.1% of trials started in 2013–14 were terminated within 2 years, against 7.4% of those started in 2019–20.
Tested on trials that started in 2015–2016, after training on 2008–2014. The score ranks trials; read it as a percentile, not a promise. Reasons describe the model, not causes of termination.